NMDA enhances calcium uptake in isolated mitochondria
نویسندگان
چکیده
Background: The accumulation of calcium by mitochondria regulates cell survival. Results: Purified mitochondria exhibit increased calcium uptake in the presence of NMDA receptor agonists. Conclusion: Functional NMDA-like receptors may be present on mitochondria. Significance: Learning how NMDA facilitates mitochondrial calcium uptake provides a new dimension to the understanding of cellular homeostasis and response to noxious stimuli.
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